BCIG SPEAKER EVENT: "Computer
Models of Stress, Allostatic Load, and Chronic Degenerative Diseases"
Clinical
Center (Building 10) Medical Board Room (Room 2C116)
- view the seminar archive
DESCRIPTION: The nature of disease has changed. Now chronic, complex
disorders, involving derangements of multiple body processes, multiple drug
treatments, and myriad interactions among those processes and the drugs used to
treat them, have come to the fore, posing enormous personal and societal
burdens. Scientific integrative medicine is not a discipline, a group of
disorders, or a method of treatment, but an approach, a way of thinking, which
emphasizes disorders of the multiple interacting systems that regulate the
body’s “inner world.” Scientific integrative medicine research uses systems
concepts to explain diseases in terms of interactions among genetic makeup, life
experiences, drug treatments, and time, with the goal of developing strategies
to treat, prevent, or palliate multi-system disorders. In this talk I present
some of the concepts of scientific integrative medicine and computer models that
apply them to understand stress, allostatic load, and acute and chronic
disorders."
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3:00 - 4:30 pm September 21, 2006
David S. Goldstein M.D., Ph.D.,
Section Chief, Clinical Neurocardiology Section, Clinical Neurosciences Program,
DIR, NINDS, NIH.
Dr. Goldstein graduated from Yale College and received an MD-PhD from Johns
Hopkins. After internal medicine training at the University of Washington, in
1978 he came to the NIH as a Clinical Associate in the National Heart, Lung, and
Blood Institute, obtaining tenure as a Senior Investigator in 1984. He joined
the NINDS in 1990 to lead the Clinical Neurochemistry Section. In 1999 he
founded and since then has headed the Clinical Neurocardiology Section, an
independent Section in the NINDS. He has received Yale’s Angier Prize for
Research in Psychology, the Laufberger Medal of the Czech Academy of Sciences,
the Presidential Executive Director’s Award of the National Dysautonomia
Research Foundation, two NIH Merit Awards, and the NIH Distinguished Clinical
Teacher Award. He is a Fellow of the American College of Physicians and of the
American Heart Association and a Member of the American Society of Clinical
Investigation, American Academy of Neurology, and American Physiological
Society. He sits on the Executive Boards of the American Autonomic Society, the
Association for Patient-Oriented Research, the Foundation for Catecholamine
Research, and the Autonomic Nervous System Section of the American Academy of
Neurology. He is the author of Stress, Catecholamines, and Cardiovascular
Disease (1995), The Autonomic Nervous System in Health and Disease (2001), The
NDRF Handbook for Patients with Dysautonomias (2002), and Adrenaline and the
Inner World: An Introduction to Scientific Integrative Medicine (2006). His
research on stress, catecholamine systems, dysautonomias, and clinical
neurocardiologic disorders has been published in almost 450 papers, which have
been cited more than 12,000 times. His main career goal is to use clinical
laboratory assessments of catecholamine systems to introduce scientific
integrative medicine into teaching, research, and clinical practice.
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