BCIG SPEAKER EVENT:
“Biclustering Bioinformatic Data Sets Using a Possibilistic Approach”
- view the seminar archive
Clinical
Center (Building 10) Medical Board Room (Room 2C116)
LECTURE ABSTRACT: The analysis of genomic data from DNA microarray
can produce valuable information on the biological relevance of genes and
correlations among them. In the last few years some biclustering techniques have
been proposed and applied to this analysis. Biclustering is a machine learning
task finding clusters of samples with similar characteristics together with
features creating these similarities. When applied to genomic data it can allow
us to identify genes with similar behavior with respect to different conditions.
In this talk a new approach to the biclustering problem will be introduced as an
extension of the Possibilistic Clustering paradigm. The proposed Possibilistic
Biclustering algorithm finds one bicluster at a time, by assigning to each gene
and to each condition a membership to the bicluster. Some results on
oligonucleotide microarray data sets will be presented and compared with those
obtained using other biclustering methods.
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3:00 - 4:30 pm November 29, 2007
Francesco Masulli, Ph.D., University of Genova
BIBLIOGRAPHIC NOTE: Francesco Masulli is an Associate Professor of
Computer Science with the University of Genova (Italy). He received the Laurea
degree in Physics from the University of Genova in 1976. After the military
service, he was a researcher with the Italian National Institute for Nuclear
Physics (1978-1979), and with the Ansaldo Automazione Co. (1979-1983), an
Assistant Professor with the University of Genova (1983-2001), and an Associate
Professor with the University of Pisa (2001-2005). He was also in leave as a
visiting scientist at the University of Nijmegen, Holland (1983), and at the
International Computer Science Institute in Berkeley, California (1991, 1993,
and 1994). He published more than 120 scientific papers on Machine Learning,
Neural Networks, Fuzzy Systems, Ensemble Methods, and Bionformatics and
co-edited seven books and five special issues of scientific journals on those
subjects. He serves as a co-chair of the SIG on Bioinformatics of the
International Neural Network Society (INNS) and as an Associate Editor the
international journal "Intelligent Automation and Soft Computing". His previous
duties include the chairing of the 2002 Course of the International School on
Neural Networks "E.R.Caianiello" on "Ensemble Methods in Learning Machines”, and
of some editions of the International Workshop on Fuzzy Logic and Applications (WILF)
and of the International Meeting on Computational Intelligence Methods for
Bioinformatics and Biostatistics (CIBB).
SPEAKER CONTACT INFORMATION:
Francesco Masulli
DISI - Dept Computer and Information Science
University of Genova
Via Dodecaneso 35, 16146 Genova, ITALY
E-mail: masulli@disi.unige.it
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