BCIG TUTORIAL:
"Bridging the Gap between Biology and Computation: Microarray Analysis from
Multiple Sources and Different Platform Generations"

- view the seminar archive
Clinical
Center (Building 10) Medical Board Room (Room 2C116)
DESCRIPTION: Microarrays
allow scientists to survey and compare simultaneous
activity of thousands of genes in normal and diseased
tissues. When properly used, they have the potential to
improve diagnostic techniques and identify promising new
targets for therapy. Two topics will be discussed. The
first topic details efforts to combine previously
published microarray data from several different sources
assayed on two different generations of Affy chips to
ask a new biological question. The second topic concerns
the collaboration of groups (teams) that speak different
languages and think about problems in different ways. It
is suggested that good collaboration among such team
members is required in order to successfully analyze
high dimensional data in biologically meaningful ways.
(This has been a major theme in BCIG for years!) The
speaker’s laboratory has tried to bridge these
differences with reasonable success over the past 5
years.
REGISTRATION: As with all BCIG
events, registration is not required. Just show up
happy.
WEBCASTING: This event will be
web cast live and be made available for post program
viewing on the BCIG web site (www.nih-bcig.org).
To get more information about our webcasting service,
please contact Meeting Master Carl Leonard by e-mail:
cleonard@lired.com
or by calling him on 301-496-0191. NIH CONTACT: Jim
DeLeo, 301-496-3848,
jdeleo@nih.gov
REFRESHMENTS: Bring refreshments
if you would like. There is an open cafeteria near the
meeting room.
BCIG WEB SITE:
www.nih-bcig.org
NIH VISITOR INFORMATION:
http://www.nih.gov/about/visitor/
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3:00 - 4:30 pm June 8, 2006
Louise C. Showe, Ph.D.
Wister Institute, Philadelphia
SPEAKER: Louise C.
Showe, has a Ph.D. in biology from the University of
Pennsylvania. She now leads the Molecular and Cellular
Oncogenesis Program at the Wister Institute in
Philadelphia. Her group is using DNA microarray
technology to better understand a number of diseases
and conditions in which changes in the activity of
multiple genes are involved. Among these are a type of
cancer known as cutaneous T-cell lymphoma, septic
shock, multiple sclerosis, and even obesity.
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