Biomedical Computing Information Group BCIG

 

BCIG TUTORIAL: "Bridging the Gap between Biology and Computation: Microarray Analysis from Multiple Sources and Different Platform Generations"

- view the seminar archive

Clinical Center (Building 10) Medical Board Room (Room 2C116)

DESCRIPTION: Microarrays allow scientists to survey and compare simultaneous activity of thousands of genes in normal and diseased tissues. When properly used, they have the potential to improve diagnostic techniques and identify promising new targets for therapy. Two topics will be discussed. The first topic details efforts to combine previously published microarray data from several different sources assayed on two different generations of Affy chips to ask a new biological question. The second topic concerns the collaboration of groups (teams) that speak different languages and think about problems in different ways. It is suggested that good collaboration among such team members is required in order to successfully analyze high dimensional data in biologically meaningful ways. (This has been a major theme in BCIG for years!) The speaker’s laboratory has tried to bridge these differences with reasonable success over the past 5 years.

REGISTRATION: As with all BCIG events, registration is not required. Just show up happy.

WEBCASTING: This event will be web cast live and be made available for post program viewing on the BCIG web site (www.nih-bcig.org). To get more information about our webcasting service, please contact Meeting Master Carl Leonard by e-mail: cleonard@lired.com or by calling him on 301-496-0191. NIH CONTACT: Jim DeLeo, 301-496-3848, jdeleo@nih.gov

REFRESHMENTS: Bring refreshments if you would like. There is an open cafeteria near the meeting room.

BCIG WEB SITE: www.nih-bcig.org

NIH VISITOR INFORMATION: http://www.nih.gov/about/visitor/ 

3:00 - 4:30 pm June 8, 2006

Louise C. Showe, Ph.D.
Wister Institute, Philadelphia

SPEAKER: Louise C. Showe, has a Ph.D. in biology from the University of Pennsylvania. She now leads the Molecular and Cellular Oncogenesis Program at the Wister Institute in Philadelphia. Her group is using DNA microarray technology to better understand a number of diseases and conditions in which changes in the activity of multiple genes are involved. Among these are a type of cancer known as cutaneous T-cell lymphoma, septic shock, multiple sclerosis, and even obesity.

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