2008:   Jan  Feb  Mar  Apr  May  Summer  Sep  Oct  Nov  Dec

 

NIH Biomedical Computing Interest Group (BCIG)

 

May 2008 News Letter

 

 

 

Jim DeLeo, editor  jdeleo@nih.gov,  301-496-3848

 

Carl Leonard, associate editor  cleonard@lired.com, 301-496-0191

 

BCIG 2008 Tentative Program

 

BCIG  Archived Webcasts

 

BCIG Website

 

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BCIG May 2008 Events

 

In May 2008 BCIG is featuring the following two events in the NIH Clinical Center (Building 10) Medical Board Room (Room 2C116):

(1)  May 8, 3:30 to 5:00 p.m.: A lecture entitled “Irresponsible Practices in Technical Professions: Heuristics for Leading the Change,” by Dev Raheja.

(2)  May 22, 5:30 to 7:00 p.m.: A book club meeting in which “Two’s Company; Three Is Complexity” will be reviewed live by the author Neil Johnson.

 

file:///C:/Documents%20and%20Settings/deleoj/Local%20Settings/Temporary%20Internet%20Files/OLK8/DevRahejaPicture.jpg   Two's Company, Three is Complexity   The image “http://www.physics.miami.edu/~njohnson/johnson.jpg” cannot be displayed, because it contains errors.

                          (1)                               (2)

                                                                                         

Click the above images for more information as well as www.nih-bcig, the BCIG web site.

 

 

 

Title: User-Friendly Cyberinfrastructures and

Their Utility for Scholarly Knowledge Management

 

 

 

Dr. Katy Borner

 

Where:  NIH Clinical Center, Hatfield 4-3330

 

When:  1:30 – 2:30 PM, Tuesday, May 6, 2008

 

 

 

“The Forgotten Revolution: The Early History of

 NIH Biomedical Computing”  

 

 

The DeWitt Stetten Jr. Annual Lecture by:  Joseph A. November, Ph.D.

 

Where:  NIH Clinical Center, Hatfield 2-3750

 

When:  3:30 – 4:30 PM, Friday, May 16, 2008

 

At NIH today, digital electronic computers are a vital, necessary component of almost all aspects of research and administration. However, there was nothing inevitable about NIH’s adoption of computers or the ways the machines came to be used. As late as 1956, the majority of NIH’s leadership was firmly against dedicating resources to computing in research. It took a hard-fought campaign throughout the late 1950s and early 1960s, led by Drs. Frederick Brackett and Arnold “Scotty” Pratt, and supported by Director James Shannon, to overcome NIH’s reluctance to adopt the new technology.  The campaign to bring computers to NIH may be long forgotten, but its consequences profoundly altered not only biomedical coputing beyond the NIH campus but also computing in general. This lecture will cover three interconnected stories. First, it will examine how the Division of Computer Research and Technology (now CIT) grew out of Brackett and Pratt’s long struggle to computerize research at NIH. Second, it surveys the far-reaching activities of the Advisory Committee on Computers in Research (NIH-ACCR), which was established in 1960 and generously funded by the U.S. Senate for the purpose of introducing computers to laboratories and hospitals worldwide. Third, it describes NIH’s important but seldom-discussed role in the development of the Laboratory Instrument Computer (LINC), a small, general-purpose, real-time digital computer built in 1963 at MIT especially for biomedical researchers; the roots of many aspects of personal computing can be traced back to the LINC

 

BCIG will record and archive this event for post session playback.

 

 

Frontiers of Statistical, Mathematical & Computational Sciences (SMCS)

Where:

The George Washington University

Room 652, Duques Hall

2201 G Street NW

Washington, DC

 

When:  9:15 AM – 4:30 PM, Tuesday, May 20, 2008

 

More Information: http://www.altum.com/bcig/news/minisymposium1.htm

 

 

Questioning Artificial Intelligence

 

      

 

 

At the May 27, 2008 BCIG Book Club meeting, we reviewed the book “Introducing Artificial Intelligence” by Henry Brighton & Howard Selina. Each of the 11 BCIG volunteers who reviewed the book submitted a question for the dialogue portion of the meeting that followed the initial book review portion. The following is an abridged summary of the questions submitted:

 

What does “knowing” mean? How complex must a machine be in order to be an AI? Why is it taking so long for progress in AI? Why can’t we be more patient? How can we build AI’s and robots that are more robust, more generally intelligent? Will AI lead to improved intelligent agent communication?   Is human knowledge limiting what we can accomplish with AI in medical applications?  Will people trust AI provided medical advice? Are AI principles applicable to chemical logic?

 

For the full text of the questions submitted, click on the cartoon above.  If you would like to send in answers to any of the questions please send them to Jim DeLeo jdeleo@nih.gov.  He  will compile all answers received and post them in a future BCIG news letter. 

 

Josh Storrs Hall author of “Beyond AI: Creating the Consequence of the Machine” came to the NIH on November 1, 2007 to review and discuss his book at a BCIG Book Cub meeting.  Here is the link for information and a rerun of that event:

NOV 1 BCIG Book Club Event: *Beyond AI: Creating the Conscience of the Machine” (Author Josh Hall will be present.) by Josh Storrs Hall
5:30 to 7:00 p.m.

- view the seminar archive

Josh has kindly written and sent us great answers to our AI questions.  To see his answers click on the picture of Josh and his friend at the top of this article.  Thanks Josh!

Professor Lotfi Zadeh, inventor of fuzzy logic, gave an NIH BCIG lecture entitled “ “ on March xx, 2—8.  Here is the link for information and a rerun of that event:

APR 10 LECTURE “Human Intelligence and Machine Intelligence: The Interface” Lotfi Zadeh, speaker

Professor Zadeh also kindly provided us some excellent answers to the AI questions.  To see Prof. Zadeh’s answers click on his picture above.  Thank you Prof. Zadeh for your great answers!

 

 

Questioning Invented Reality

 

 

At the April 24, 2008 BCIG Book Club meeting, we reviewed the book “The Invented Reality: How Do We Know What We Believe We Know?” (Contributions to Constructivism)” edited by Paul Watzlawick.  Each of the 11 BCIG volunteers who reviewed the book submitted a question for the dialogue portion of the meeting that followed the initial book review portion. What follows is an abridged summary of the questions submitted.

 

Questions Invented by Presenters: The book is about constructivism, which is also known as “reality research.”  It claims we don’t discover reality but that we invent or construct it.  So the basic questions are how do we know what’s real and are our lives constructed realities just like fiction?  Our resident cynic asks if constructivism is an obsolete philosophy that just promotes scorn of modern science and rationality?  Practical questions that emerged were: (1) How do you know that what you find when you mine data is truly meaningful and useful?” (2) Can knowledge of the ‘imperfection’ of the human mind help us build more intelligent machines?  (3) What guides our thinking and facilitates our survival?  Other interesting and humorous questions include: (1) Does anybody take Aristotle seriously anymore? (2) What’s the reality of an ideologist? (3) Is mathematics an invention? (4) What is the relationship of constructivism to comedy, magic and shamanism? (5) Does anyone in the audience have a question? (6) What’s a ‘question’?” (7) Does the apple really posses perceived and even unperceived properties? (8) How do you tell the difference between a red traffic light and a brothel? (9) Why were we in Vietnam? (10) Do any of these questions make sense and if so what does “make sense” mean?

 

Here’s a link to the full text questions:  http://www.altum.com/bcig/news/TIRQ.htm

 

 

 

The NIH Clinical Center

Department of Clinical Research Informatics

 Scientific Computing Section

 

                                                               

 

(Click here or on the picture above for more information.)

 

Scientific Computing Section Mission Statement: “To support and promote the goals of DCRI by seeking and engaging in active research and collaborative work within the NIH community as well as with academia and industry - work in which knowledge in the biomedical and computing sciences is advanced, and from which practical results that directly lead to better health for everyone are realized.”

 

To discuss possible collaborations please contact:

 

Jim DeLeo,

E-mail: jdeleo@nih.gov,

Telephone: 301-496-3848

 

BCIG Member Selected TED Talks

Craig Venter: On the verge of creating synthetic life

 

 

About this talk: Can we create new life out of our digital universe?" asks Craig Venter. And his answer is, yes, and pretty soon. He walks the TED2008 audience through his latest research into "fourth-generation fuels" -- biologically created fuels with CO2 as their feedstock. His talk covers the details of creating brand-new chromosomes using digital technology, the reasons why we would want to do this, and the bioethics of synthetic life. A fascinating Q&A with TED's Chris Anderson follows (two words: suicide genes). Disclosure notice: TED Curator Chris Anderson was an early private investor in Craig Venter's company Synthetic Genomics. His ownership position is less than 1% of the company.

About Craig Venter:  In 2001, Craig Venter made headlines for sequencing the human genome. In 2003, he starting mapping the... Read full bio

 

(Thanks for calling our attention to the above Pete!)

 

 

Your Genes are not your fate, Dean Ornish, M.D

 

 

Anne Ornish and her husband Dr. Dean Ornish

 

.My Stroke of Insight, Jill Bolte Taylor


 

Jill Bolte Taylor

Neuroanatomist Jill Bolte Taylor had an opportunity few brain scientists would wish for: One morning, she realized she was having a massive stroke. As it happened -- as she felt her brain functions slip away one by one, speech, movement, understanding -- she studied and remembered every moment. This is a powerful story about how our brains define us and connect us to the world and to one another.

(Thanks for calling our attention to the above Praveen!)

 

 

Smart-Marts TM

 

We (Scientific Computing Section) have coined and trademarked “Smart-Mart TM.” A “Smart-Mart TM” is a data mart (mini data warehouse) with built in intelligence (application programs).  In the NIH Clinical Center Department of Clinical Research Informatics Scientific Computing Section where Carl Leonard and I work, we are building Smart-Marts TM to data mine individual principle investigators’ data to find new knowledge, suggest interesting new hypotheses and reorganize data in such a way that it makes not so obvious embedded knowledge more apparent.  Carl and I are open to inquiries about this work.

 

 

The Virtual University

 

Last November’s BCIG speaker Professor Francesco Masulli, a computer scientist at the Italy’s University of Genova and I have agreed to experiment with our version of the “Virtual University.”  The general idea is for professors to collaborate with domain workers for the purpose of assigning interesting practical problems to students.  Everybody gains.  Professors get projects for their students, domain workers get some practical work done and students get scholastic credit for their work.  Franco and I will start with one graduate student.  I will offer the graduate student a choice of software development projects, such as constructing ROC and analyzing plots, interactive parallel coordinates, time-varying star glyph images, classification or clustering production run systems.  A side benefit for me and the student is that I get to learn more Italian from the student and the student gets to learn Philadelphia English from me.  We can use Skype so we have a better sense of presence of the other.  Please let me know if you have any interest in this prototype initiative.

 

 

BCIG Member Suggested Books

 

A Life Decoded: My Genome: My Life (Hardcover)
by J. Craig Venter

 

In case you did not see this book, a very interesting read. Goes into how science works/doesn't work/politics of science/large organization/his days in the medical corp in Vietnam, the human genome, etc.

[It is in the
Montgomery County library.]

 
 

 

 

Beautiful Pictures

 

 

 

On the Lighter Side

 

Demetri Martin – a very funny guy!

 

 

 

Swiss Spaghetti Harvest 1957

 

 

 

Personals

 

(Send your personals to Jim DeLeo, jdeleo@nih.gov for posting in future BCIG newsletters.)

 

 

Position Sought

 

 

Vladimir Goodkovsky, Ph.D., Computer Scientist

 

 

I Need Help with Italian

 

 

 I would like to have lunch/coffee with native speakers of the Italian language for the purpose of improving my speaking and understanding of the Italian language.  Jim DeLeo, 301-496-3848, jdeleo@nih.gov.

 

 

Do You Have Something to Say?

 

Please send short and to-the-point relevant articles like the ones above to me for posting in upcoming BCIG news letters. 

 

Jim DeLeo

 jdeleo@nih.gov

301-496-3848